Thrombotic Risk DNA Test

Are you at increased risk of abnormal blood clots? The DNA Thrombotic Risk Test can tell you just that.

  Detects variant in F5, F2 and MTHFR genes

 Buccal swab sample collection


Free Shipping • FSA / HSA accepted

Free shipping on all orders within the U.S.

What you get with this test

Detailed Description

Thrombosis is the formation of a blood clot inside a blood vessel, preventing the flow of blood through the circulatory system. Deep vein thrombosis (DVT) is the most common form of venous thrombosis (blood clot). DVT refers to a clot in a deep vein and it often happens in the leg. Symptoms in the affected area include pain, swelling, redness and warmth.

If you suspect a DVT you should contact a doctor as soon as possible, because sometimes the clot may break loose and travel to other parts of the body.

If the clot travels to the lungs, it can block essential blood vessels. This life-threatening complication is known as a pulmonary embolism (PE). Symptoms include a sudden shortness of breath, chest pain, coughing up blood-streaked mucus and a rapid heartbeat.

If the clot travels to the brain, it is also extremely dangerous and can potentially cause a cerebral venous thrombosis. Symptoms include impaired speech, difficulty moving parts of the body, vision problems and severe headaches.

Every year, more people die from a blood-clotting problem than breast cancer and HIV combined. All that is needed is a simple mouth swab to uncover your risk with this DNA test.

The Genetics

Genetic changes in three genes are analyzed in this thrombotic risk test. Each change contributes to an increased risk of thrombosis.

Variants Tested:

  • F5 – the Factor V Leiden mutation (1691G>A)
  • F2 – the prothrombin mutation (20210G>A)
  • MTHFR – two mutations (677C>T and 1298A>C)

We inherit two copies of each gene – one from each parent. Therefore we can inherit two normal copies of a gene (homozygous normal), two copies that carry a genetic mutation (homozygous mutant), or one normal copy and one mutated copy (heterozygous). This means that we can inherit several different combinations of the F5F2 and MTHFR genes. Each combination is associated with a different risk of thrombophilia.

Reducing your Risk of a Blood Clot:

  • Maintain a healthy body weight
  • Follow a healthy diet
  • Increase your blood flow with exercise
  • Avoid extended periods of immobility
  • Avoid smoking
  • Reduce homocysteine levels by getting plenty of folate and other B vitamins
  • Wear compression stocking on long flights
  • If your risk is very high, seek medical treatment (e.g. anticoagulants)

CLIA Certified

All Genofit tests are guaranteed to be processed by a CLIA certified laboratory–the same type of certification as hospital laboratories.

Physician Reviewed

Genofit tests are reviewed and approved by a third-party independent physician licensed to practice within your state.

HIPAA Compliant

Genofit takes measures to guarantee your privacy. Your personal data is securely stored and will not shared with any third-party without your permission.

Get Started in 3 Easy Steps​

Get Started in 3 Easy Steps

1. Activate Kit

Activate your kit online at by entering the unique activation code found inside your kit.

2. Collect & Mail Sample

Simply collect your sample at home, then mail your sample directly to the lab with free return shipping.

3. View Results

Receive your results within 5-7 business days after the lab receives your kit.


Here are the answers to the most frequently asked questions about this test.

Yes, your results are 100% confidential. No one will be able to access your account or your results unless you give them your confidential account login. You can change the password to your account at any time. Please remember to safeguard your login information and not share it with anyone.
Testing begins immediately the day that your samples arrive at the laboratory. In some special situations, additional testing may be required, which could increase the turnaround time by a few extra days. You can check the status of your test online 24/7 using your secure account login. Your test report is released immediately once testing is complete.
Drinking or eating will not change the results in any way. The reason that you are not supposed to drink or have anything in the mouth for an extended period prior to collection is to ensure that we have enough buccal cells to complete the test. If there are not enough cells to complete the test, then the results will not be released and a recollection will be required.
No. You can send the kits back to the laboratory using any shipping method of your choosing. Please be advised that if you do not use the included prepaid return mailer to ship your samples, it is your responsibility to ensure that your samples arrive at the laboratory. We will not be able to provide assistance for shipments that do not use our prepaid return mailer.

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