Physical Fitness DNA Test

Get the most out of your workout. Identify how your DNA influences your athletic ability, response to exercise, injury risk and pain tolerance. Start a personalized exercise plan based on your DNA to get the best results.


  • Endurance ability
  • Power training
  • Strength training
  • Response to exercise
  • Sports-related injury risk
  • Your motivation to exercise

Buccal swab sample collection


Free Shipping • FSA / HSA accepted

Free shipping on all orders within the U.S.

What you get with this test

Detailed Description

Are you struggling to improve your fitness?

Or maybe you are just interested to know why you are a great sprinter but have a tough time finishing a 10K race. It all comes down to genetics.

Your genes influence your athletic ability, response to exercise, injury risk and pain tolerance. This genetic test gives you the opportunity to create a personalized exercise plan based on your genetics, so you can get the most benefit out of your exercise routine.

The Genetics

Studies show that athletes carry genetic variants that give them an advantage in their choice of athletics. This means the DNA changes that are most prevalent in endurance athletes can be very different from the variants found in sprinters and other power athletes.

An understanding of your genetics can help you identify the sports that you are better suited for. It also gives you a chance to personalize your exercise plan and health goals. The variants included in this panel were studied in Caucasian populations. The same association may not be apparent in other ethnicities.

What’s Tested

Athletic Endurance

Endurance is the ability to continue exercising for an extended period. Endurance events include long-distance running, swimming, cycling, mountain climbing and rowing. Variants Affecting Endurance:

• PPARD – burning fat for energy
• VEGFA – blood vessel formation to improve oxygen supply
• ACE – blood pressure regulation and muscle efficiency
• ADRB2 – turning off the fight or flight response
• PPARA – slow-twitch versus fast-twitch muscle fibres

Response to Exercise

Not everyone responds to exercise the same. Some people see greater benefits from endurance training, while others benefit more from strength training. Your exercise response is influenced by genetic variations of:

• PPARGC1A – aerobic capacity improvements
• PPARD – increases in “good”
• HDL-cholesterol
• MCT1 – ability to use lactate as an energy source

Strength Training

Strength exercises use resistance to induce muscular contraction, which builds the strength and size of skeletal muscles. Variants Affecting Muscular Strength:

• ACVR1B – muscle signalling cascade that controls muscle mass and muscle strenght
• IL6 – messenger molecule and contributes to muscle growth

Athletic Power

Power exercises combines strength with speed, applying strength in a quick motion. For example, a sprinter requires strength and speed for a rapid acceleration, while a baseball pitcher requires a very strong arm that can rapidly rotate to pitch as fast as 100 mph! Variants Affecting Power:  – blood pressure regulation and growth hormone levels

• ACTN3 – the “sprinter” gene
• AGT – blood pressure regulation and growth hormone levels

Motivation, Recovery, Injury Risk and Pain Tolerance

Motivation, recovery, injury risk and pain tolerance are all influenced by the following genetic variations:

• BDNF – exercise motivation
• CRP – heart rate recovery
• COL1A1 – risk of soft tissue injury
• COL5A1 – risk of Achilles tendinopathy
• COMT – pain tolerance and required morphine dose

CLIA Certified

All Genofit tests are guaranteed to be processed by a CLIA certified laboratory–the same type of certification as hospital laboratories.

Physician Reviewed

Genofit tests are reviewed and approved by a third-party independent physician licensed to practice within your state.

HIPAA Compliant

Genofit takes measures to guarantee your privacy. Your personal data is securely stored and will not shared with any third-party without your permission.

Get Started in 3 Easy Steps​

Get Started in 3 Easy Steps

1. Activate Kit

Activate your kit online at by entering the unique activation code found inside your kit.

2. Collect & Mail Sample

Simply collect your sample at home, then mail your sample directly to the lab with free return shipping.

3. View Results

Receive your results within 5-7 business days after the lab receives your kit.


Here are the answers to the most frequently asked questions about this test.

Yes, your results are 100% confidential. No one will be able to access your account or your results unless you give them your confidential account login. You can change the password to your account at any time. Please remember to safeguard your login information and not share it with anyone.
Testing begins immediately the day that your samples arrive at the laboratory. In some special situations, additional testing may be required, which could increase the turnaround time by a few extra days. You can check the status of your test online 24/7 using your secure account login. Your test report is released immediately once testing is complete.
Drinking or eating will not change the results in any way. The reason that you are not supposed to drink or have anything in the mouth for an extended period prior to collection is to ensure that we have enough buccal cells to complete the test. If there are not enough cells to complete the test, then the results will not be released and a recollection will be required.
No. You can send the kits back to the laboratory using any shipping method of your choosing. Please be advised that if you do not use the included prepaid return mailer to ship your samples, it is your responsibility to ensure that your samples arrive at the laboratory. We will not be able to provide assistance for shipments that do not use our prepaid return mailer.

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